-AFC Leopards
- the first team to take part in CAF Champions League in Ghana :
-Real Republicans
- the first team to take part in CAF Champions League in Tanzania :
- Young Africans
- the first team to take part in CAF Champions League in Tunisia :
-Esperance
- the first team to take part in CAF Champions League in Nigeria :
- Stationery Stores
- the first team to take part in CAF Champions League in Egypt :
- Olympic Club
- the first team to take part in CAF Champions League in Algeria :
- CR Belcourt
- the first team to take part in CAF Champions League in Morocco :
- FAR Rabat
- the first team to take part in CAF Champions League in Ethiopia :
- Cotton Factory Club
- the first team to take part in CAF Champions League in Mali :
- Stade Malien
- the first team to take part in CAF Champions League in Senegal :
- Espoir de Saint-Louis
- the first team to take part in CAF Champions League in Guinea :
- Sily CK
- the first team to take part in CAF Champions League in Liberia :
- Invincible Eleven
- the first team to take part in CAF Champions League in Ivory Coast :
- ASEC Mimosas
- the first team to take part in CAF Champions League in Cameroon :
- Oryx Douala
- the first team to take part in CAF Champions League in Congo :
- Diables Noirs
- the first team to take part in CAF Champions League in Gambia :
- Augustinians FC
- the first team to take part in CAF Champions League in Uganda :
- Prisons FC Kampala (Maroons FC)
- the first team to take part in CAF Champions League in Sudan :
- Al-Hilal
- the first team to take part in CAF Champions League in B.Faso:
- Etoile Filante
- the first team to take part in CAF Champions League in DR Congo:
- CS Imana (DCMP)
- the first team to take part in CAF Champions League in Zambia :
- Kabwe Warriors
- the first team to take part in CAF Champions League in South Africa :
- Mamelodi Sundowns
